Donny van de Beek will play no part at Euro 2020 after the Netherlands midfielder picked up an injury.
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Van de Beek missed the win over Georgia on Sunday and was then seen training alongside Matthijs de Ligt, who has a groin issue.
On Tuesday, Ons Oranje have confirmed that Van de Beek has been ruled out of the tournament and will now leave the Netherlands training camp.
It is a major blow for the Manchester United midfielder, who was hoping to have a positive tournament after a tough season domestically.
Frank de Boer will not call-up a replacement for the 24-year-old.
This is the chance to call upon either Karsdop or Hateboer for the Right def for 5-3-2.
Big loss but it is better for De Boer to take Karsdorp or Hateboer.